20+ years of mass drug administration against urogenital schistosomiasis on the Zanzibar islands: Is praziquantel still efficacious?
A longitudinal study conducted on Pemba Island between October 2024 and March 2025 found that praziquantel remains highly efficacious against urogenital schistosomiasis following over 20 years of mass drug administration, with egg reduction rates exceeding the WHO's 90% threshold, although efficacy was slightly lower and negatively associated with pre-treatment infection intensity in one school.